Phase separation of Nur77 mediates celastrol-induced mitophagy

nuri77Nur77 responds to a wide range of physiological molecules and stimuli. 4, 14 These snals quickly induce Nur77 expression and stimulate its transcriptional activity; Nur77Overview of the antiinflammatory snaling pathway of the orphan nuclear receptor Nur77 in EC. LPS induces an increase of Nur77 expression that negatively regulates endothelial